Week 13 action is finally here!

After a big week of storylines and preparation, kickoff for this weekend’s B1G action is finally here. Up first is one of the biggest games of the entire weekend with Ohio State taking on Penn State in Columbus.

Elsewhere, Michigan is trying to keep a hot streak rolling into next week’s rivalry game while Indiana is trying to come up with a signature upset to cap its memorable season.

RELATED: The best College GameDay signs from Columbus for Week 13

It is a full weekend of B1G action with all 14 teams squaring off in conference play. As we get set for the games, here are the picks from ESPN’s College GameDay, including those made by guest-picker Eddie George:

Desmond Howard: Illinois (over Iowa), Michigan (over Indiana), Ohio State (over Penn State)

George: Iowa (over Illinois), Michigan (over Indiana), Ohio State (over Penn State)

Kirk Herbstreit: Illinois (over Iowa), Michigan (over Indiana), Ohio State (over Penn State)

RELATED: Ohio State, Penn State players need separating during pre-game scuffle

Lee Corso: Iowa (over Illinois), Indiana (over Michigan), Ohio State (over Penn State)

David Pollack: Ohio State (over Penn State)

Chris “Bear” Fallica: “Lean towards taking the big number (-18) for Ohio State.”