It’s never too early to start looking at some opening lines for the upcoming college football season.

At this point in the offseason, usually only the biggest matchups of the upcoming season are released. And that’s the case for South Point Casino, which recently released the opening lines for some of the most important games for 2021.

That includes some of the most highly-anticipated nonconference games this fall.

With over three months still remaining until the season officially kicks off, there’s a good chance that these lines change quite a bit. Still, it’s interesting to see where the spreads are set and which teams will be favored in the biggest contests of the season.

Here’s a look at the most-interesting B1G nonconference games and the opening lines, via South Point Casino in Las Vegas:

Saturday, Sept. 11

Iowa vs. Iowa State (-7)

Oregon vs. Ohio State (-13)

Washington vs. Michigan (-3)

Saturday, Sept. 18

Auburn vs. Penn State (-3.5)

Purdue vs. Notre Dame (-10)

Cincinnati (E) vs. Indiana (E)

Nebraska vs. Oklahoma (-19)

Saturday, Sept. 25

Notre Dame vs. Wisconsin (-4)