The Indiana Hoosiers were looking to start the 2021 season strong after a great 2020 college football season. On Saturday, the #17 Indiana Hoosiers kicked off their 2021 season with a disappointing 34-6 road loss to the #18 Iowa Hawkeyes.

According to Indy Star college reporter Zach Osterman, the Hoosiers had their worst loss by point margin in a season-opener since the 2017 matchup at home against the #2 Ohio State Buckeyes with a 49-21 loss. This loss also matched their other worst season-opening game since 1957 when they lost at the #4 Michigan State Spartans 54-0.

The Hoosiers came into this game as a 3.5-point underdog to the Hawkeyes, but they fell apart quickly by halftime with a 31-3 score. Indiana was outgained by Iowa in total yards accounted for 303-to-233 and first downs accounted for 18-to-11. In the first game since suffering an ACL injury on November 30th against the Maryland Terps, quarterback Michael Penix Jr. threw three interceptions against the Hawkeyes.

The Hoosiers (0-1) will host the Idaho Vandals (1-0) next Saturday in their home game of the season.