Indiana’s going to be without a critical cog against the defending national champions, and perhaps the rest of 2015.

The program announced on Tuesday that defensive tackle Darius Latham is suspended “immediately and indefinitely from competition with the football team pending the resolution of a proceeding with Indiana University Office of Student Ethics,” per a release from the university.

IU said in a release it would not have any further comment on the matter.

It’s the second suspension of the season for the Indianapolis native. He missed the season opener against Southern Illinois because of a violation of team rules.

In his three games back, Latham made his presence felt. He racked up five tackles for loss and two sacks during that time and was coming off a game at Wake Forest in which he had three TFL’s.

For an IU defense that has allowed 138.5 yards per game on the ground this year, the loss of Latham will be felt.

The Hoosiers are 4-0 for the first time since 1990 and will host No. 1 Ohio State on Saturday at 3:30 p.m. ET.