Ohio State may have to try to keep its undefeated season alive without some key players on both sides of the football.

Thursday, Bill Rabinowitz of the Columbus Dispatch tweeted out some of the notable depth chart concerns for Ohio State’s Friday night clash with Northwestern. Several players are listed as either out or game-time decisions for the B1G contest.

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Linebacker Baron Browning will be out for the game, as well as offensive lineman Josh Alabi and tight end Jake Hausmann. Offensive lineman Thayer Munford, H-Back C.J. Saunders and linebacker Teradja Mitchell are all listed as game-time decisions.

Browning has been a key player at the linebacker position for the Buckeyes, registering 23 tackles with five stops for loss through six games. Munford would also be a significant loss, considered by some media outlets to be a midseason All-American for his play in the trenches.

Ohio State heads into Friday’s game as a four-touchdown favorite.