Penn State and Iowa will meet in Week 4 for the first time since a 2021 matchup in Kinnick Stadium. That wild top-5 matchup went in favor of the Hawkeyes, but this time Iowa must make the trek to Happy Valley.

While the rankings are a bit different this time around, it will still be a top-25 B1G crossover battle. Iowa checked in at No. 24 on the latest AP Poll while Penn State is No. 7.

In terms of the betting line, Penn State will be a heavy favorite at home for the Week 4 game. Circa Sports released opening lines Sunday afternoon with the Nittany Lions listed at -14 with a point total set at 39.5. Interested fans can head to BetMGM to get in on those odds!

While both teams are 3-0 to start the season, there’s no denying how impressive the Nittany Lions look so far. James Franklin’s squad is averaging 43.7 points per game on offense and limiting opponents to 11.7 points per game. That includes a road win against Illinois while holding the Illini to 13 points and recording 4 interceptions.

On the other side of the matchup, Kirk Ferentz’s squad is averaging 28.3 points per game and limiting opponents to 12.3 points per game. Those numbers are boosted a bit by the Hawkeyes scoring 41 against Western Michigan as QB Cade McNamara continues to find his footing after a training camp injury.

A big key to watch for this matchup is likely the health of some key players on Iowa’s offense. Starting running back Kaleb Johnson was held out of Week 3 with an ankle injury and star tight end Luke Lachey left the game on crutches. Ferentz indicated after the game that Lachey’s injury appeared serious.

Saturday’s game is set for a 7:30 pm ET kickoff with the broadcast on CBS. It will also be the annual White Out matchup for Penn State.